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Search Results for " ep4 receptor antagonist 1 "

5

Compounds

Cat No. Product Name Synonyms Targets
T11211 EP4 receptor antagonist 1 Prostaglandin Receptor
EP4 Receptor Antagonist 1 is a highly potent and selective competitive prostanoid EP4 receptor antagonist, effective for cancer immunotherapy. It inhibits both human and mouse EP4 receptors with IC50 values of 6.1 nM and...
TQ0292 Grapiprant AAT-007,RQ-00000007,CJ-023423 Prostaglandin Receptor
Grapiprant (AAT-007) is a selective EP4 receptor antagonist. Grapiprant displaces [3H]-PGE2 (1 nM) binding to dog recombinant EP4 receptor (IC50: 35 nM, Ki: 24 nM).
T60840 EP4 receptor antagonist 4
EP4 receptor antagonist 4 is an agonist of EP4 receptor (human pEC 50 = 6.3) [1].
T14500 BAY-1316957 Prostaglandin Receptor
BAY-1316957 is a highly potent and selective EP4 receptor antagonist. With an IC50 of 15.3 nM. Good oral bioavailability[1].
T83779 EP4 Antagonist 14 Prostaglandin E2 Receptor 4 Antagonist 14,PGE2 Receptor 4 Antagonist 14
EP4 antagonist 14 is a prostaglandin E2 receptor subtype EP4 antagonist, demonstrating an IC50 of 1.1 nM in a HEK293 human receptor reporter assay and blocking β-arrestin recruitment due to PGE2 with an IC50 of 0.9 nM. A...
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