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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11211 | EP4 receptor antagonist 1 | Prostaglandin Receptor | |
EP4 Receptor Antagonist 1 is a highly potent and selective competitive prostanoid EP4 receptor antagonist, effective for cancer immunotherapy. It inhibits both human and mouse EP4 receptors with IC50 values of 6.1 nM and... | |||
TQ0292 | Grapiprant | AAT-007,RQ-00000007,CJ-023423 | Prostaglandin Receptor |
Grapiprant (AAT-007) is a selective EP4 receptor antagonist. Grapiprant displaces [3H]-PGE2 (1 nM) binding to dog recombinant EP4 receptor (IC50: 35 nM, Ki: 24 nM). | |||
T60840 | EP4 receptor antagonist 4 | ||
EP4 receptor antagonist 4 is an agonist of EP4 receptor (human pEC 50 = 6.3) [1]. | |||
T14500 | BAY-1316957 | Prostaglandin Receptor | |
BAY-1316957 is a highly potent and selective EP4 receptor antagonist. With an IC50 of 15.3 nM. Good oral bioavailability[1]. | |||
T83779 | EP4 Antagonist 14 | Prostaglandin E2 Receptor 4 Antagonist 14,PGE2 Receptor 4 Antagonist 14 | |
EP4 antagonist 14 is a prostaglandin E2 receptor subtype EP4 antagonist, demonstrating an IC50 of 1.1 nM in a HEK293 human receptor reporter assay and blocking β-arrestin recruitment due to PGE2 with an IC50 of 0.9 nM. A... |